the effect of acidic ph on microleakage of mineral trioxide aggregate and calcium-enriched mixture apical plugs

introduction: the purpose of this laboratory study was to evaluate the effect of acidic ph on the sealing ability of calcium-enriched mixture (cem) cement and mineral trioxide aggregate (mta) apical plugs. methods and materials: seventy single-rooted human maxillary anterior teeth were recruited. the teeth were randomly divided into 4 experimental groups ( n =15), and 1 negative and 1 positive control groups of 5. the root canals were cleaned and shaped and the terminal 3 mm of the roots were resected. then mta and cem cement plugs were condensed in apical region with 3 mm thicknesses. the samples were exposed to ph values of 5.5 and 7.4. leakage was evaluated by the fluid filtration technique at 1, 7, 14, 30 day intervals. data were analyzed by the repeated measures manova, one-way anova and manova/bonferroni test. results: acidic ph significantly reduced the sealing ability of mta after 1, 14 and 30 days ( p <0.05). the rate of microleakage in cem cement samples in acidic ph was significantly greater than that in neutral ph in day 30 ( p <0.05). there was no significant difference between the sealing property of mta and cem cement at both ph levels ( p >0.05). conclusion: it can be concluded that the cem cement exhibited similar sealing ability as mta at both ph levels. in addition, an acidic ph environment reduced the sealing ability of mta and cem cement after 30 days.